bgstatslogo

Projects

 


Selection of recent projects:

Lipopredict - Prognostic value of NMR lipid subfractions on cardiovascular risk
in the LURIC study

Client: NUMARES, Regensburg, Germany

The aim of the project is to develop a novel lipid risk score including lipid subfractions measured by NMR technology in different risk settings and different patient subpopulations of the LURIC study. Renopredict - A novel biomarker score for prediction of cardiovascular risk and mortality in  diabetes patients on hemodialysis.

 

 

Renopredict - A novel biomarker score for prediction of cardiovascular risk
and mortality in diabetes patients on hemodialysis

Client: Department of Nephrology, University of Würzburg, Germany

The aim of the project is to derive a scoring system for prediction of cardiovascular risk and mortality in diabetes patients on hemodialysis. Prognostic models are derived from follow-up data of the Deutsche Diabetes Dialyse Study (4D study).


 

Plant sterols and cardiovascular risk. A meta-analysis of epidemiological studies

Client: Danone Research, Palaiseau, France

The impact of increased serum concentrations of plant sterols on cardiovascular risk is unclear. BGStats was contraczed to conduct a systematic review and meta-analysis aimed to investigate whether there is an association between serum concentrations of two common plant sterols (sitosterol, campesterol) and cardiovascular disease (CVD).

 


Quantification of HDL proteins, cardiac events and mortality in type 2 diabetes patients on hemodialysis - A Post-Hoc Analysis from the 4D Study

Client: Department of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria



There is a need for novel biomarkers related to high density lipoprotein (HDL) cholesterol HDL that better quantify the prognostic effect than the total serum concentration. We evaluated the prognostic effect of serum amyloid A (SAA) and surfactant-protein B (HDL) in patients with type 2 diabetes on hemodialysis participating in the German Diabetes and Dialysis Study (4D Study).

 

Effect of high-flux dialysis on circulating FGF-23 concentrations in ESRD patients: results from a randomised trial

Client: Department of Nephrology, University of Würzburg, Germany

In patients undergoing hemodialysis increased concentrations of circulating fibroblast growth factor-23 (FGF-23) are independently associated with cardiovascular events and mortality. We conducted a post-hoc analysis of a randomized trial (the MINOXIS study) aimed to compare the impact of high-flux versus low-flux hemodialysis on circulating FGF-23 concentrations.

 

The association between low density lipoprotein cholesterol, statins and cardiovascular events: a meta-analysis

Client: Pfizer GmbH, Karlsruhe, Germany

Bgstats Consulting was contracted to undertake a meta-analysis with the aim to to determine whether the magnitude of the risk reduction according to different cardiovascular endpoints correlates with the magnitude of the statin induced reduction of low density lipoprotein cholesterol (LDL-C).